Protein name:
Mitofusin-1 ;
Alternative:
Transmembrane GTPase MFN1 ;
Organism:
Mouse (Mus musculus).
General Annotation
Sub Unit:
Forms homomultimers and heteromultimers with MFN2. Multimerization, which is probably mediated by the coiled coil region, may play an essential role in mitochondrion fusion. Participates in a high molecular weight multiprotein complex.
Function:
Essential transmembrane GTPase, which mediates mitochondrial fusion. Fusion of mitochondria occurs in many cell types and constitutes an important step in mitochondria morphology, which is balanced between fusion and fission. MFN1 acts independently of the cytoskeleton. Overexpression induces the formation of mitochondrial networks.
Subcellular Location:
Mitochondrion outer membrane
Multi-pass membrane protein
Protein Attributes:
50:
MAETVSPLKH | FVLAKKAITA | IFGQLLEFVT | EGSHFVEATY | RNPELDRIAS |
100:
EDDLVEIQGY | RNKLAVIGEV | LSRRHMKVAF | FGRTSSGKSS | VINAMLWDKV |
150:
LPSGIGHTTN | CFLSVEGTDG | DKAYLMTEGS | DEKKSVKTVN | QLAHALHMDK |
200:
DLKAGCLVHV | FWPKAKCALL | RDDLVLVDSP | GTDVTTELDI | WIDKFCLDAD |
250:
VFVLVANSES | TLMNTEKHFF | HKVNERLSKP | NIFILNNRWD | ASASEPEYME |
300:
DVRRQHMERC | LHFLVEELKV | VSPSEARNRI | FFVSAKEVLN | SRKHKAQGMP |
350:
EGGGALAEGF | QARLQEFQNF | EQTFEECISQ | SAVKTKFEQH | TIRAKQILDT |
400:
VKNILDSVNV | AAAEKRVYSM | EEREDQIDRL | DFIRNQMNLL | TLDVKKKIKE |
450:
VTEEVANKVS | CAMTDEICRL | SVLVDEFCSE | FHPTPSVLKV | YKSELNKHIE |
500:
DGMGRNLADR | CTNEVNASIL | QSQQEIIENL | KPLLPAGIQN | KLHTLIPCKK |
550:
FDLSYDLNCH | KLCSDFQEDI | VFRFSLGWSS | LVHRFLGSTN | AQRVLLGLSE |
600:
PIFQVPRSLA | STPTAPSNPA | APDNAAQEEL | MITLITGLAS | LTSRTSMGII |
650:
VVGGVIWKTV | GWKLISVTLS | MYGALYLYER | LTWTTRAKER | AFKQQFVNYA |
700:
TEKLQMIVSF | TSANCSHQVQ | QEMATTFARL | CQQVDVTQKH | LEEEIARLSK |
741:
EIDQLEKIQN | NSKLLRNKAV | QLESELENFS | KQFLHPSSGE | S
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
Rat
ELISA Kit for Mouse Mitofusin-1
ELISA Kit for Mouse Mitofusin-1
ELISA Kit for Mouse Mitofusin-1
CLIA Kit for Mouse Mitofusin-1
CLIA Kit for Mouse Mitofusin-1
CLIA Kit for Mouse Mitofusin-1
Polyclonal Antibody for Mouse Mitofusin-1
Polyclonal Antibody for Mouse Mitofusin-1
Polyclonal Antibody for Mouse Mitofusin-1
Monoclonal Antibody for Mouse Mitofusin-1
Monoclonal Antibody for Mouse Mitofusin-1
Monoclonal Antibody for Mouse Mitofusin-1
Protein for Mouse Mitofusin-1
Protein for Mouse Mitofusin-1
Protein for Mouse Mitofusin-1
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA];FUNCTION;DEVELOPMENTAL STAGE;MULTIMERIZATION
strain :
FVB .
2.
"The transcriptional landscape of the mammalian genome."
Carninci P.
,
Kasukawa T.
,
Katayama S.
,
Gough J.
,
Frith M.C.
,
Maeda N.
,
Oyama R.
,
Ravasi T.
,
Lenhard B.
,
Wells C.
,
Kodzius R.
,
Shimokawa K.
,
Bajic V.B.
,
Brenner S.E.
,
Batalov S.
,
Forrest A.R.
,
Zavolan M.
,
Davis M.J.
,
Wilming L.G.
,
Aidinis V.
,
Allen J.E.
,
Ambesi-Impiombato A.
,
Apweiler R.
,
Aturaliya R.N.
,
Bailey T.L.
,
Bansal M.
,
Baxter L.
,
Beisel K.W.
,
Bersano T.
,
Bono H.
,
Chalk A.M.
,
Chiu K.P.
,
Choudhary V.
,
Christoffels A.
,
Clutterbuck D.R.
,
Crowe M.L.
,
Dalla E.
,
Dalrymple B.P.
,
de Bono B.
,
Della Gatta G.
,
di Bernardo D.
,
Down T.
,
Engstrom P.
,
Fagiolini M.
,
Faulkner G.
,
Fletcher C.F.
,
Fukushima T.
,
Furuno M.
,
Futaki S.
,
Gariboldi M.
,
Georgii-Hemming P.
,
Gingeras T.R.
,
Gojobori T.
,
Green R.E.
,
Gustincich S.
,
Harbers M.
,
Hayashi Y.
,
Hensch T.K.
,
Hirokawa N.
,
Hill D.
,
Huminiecki L.
,
Iacono M.
,
Ikeo K.
,
Iwama A.
,
Ishikawa T.
,
Jakt M.
,
Kanapin A.
,
Katoh M.
,
Kawasawa Y.
,
Kelso J.
,
Kitamura H.
,
Kitano H.
,
Kollias G.
,
Krishnan S.P.
,
Kruger A.
,
Kummerfeld S.K.
,
Kurochkin I.V.
,
Lareau L.F.
,
Lazarevic D.
,
Lipovich L.
,
Liu J.
,
Liuni S.
,
McWilliam S.
,
Madan Babu M.
,
Madera M.
,
Marchionni L.
,
Matsuda H.
,
Matsuzawa S.
,
Miki H.
,
Mignone F.
,
Miyake S.
,
Morris K.
,
Mottagui-Tabar S.
,
Mulder N.
,
Nakano N.
,
Nakauchi H.
,
Ng P.
,
Nilsson R.
,
Nishiguchi S.
,
Nishikawa S.
,
Nori F.
,
Ohara O.
,
Okazaki Y.
,
Orlando V.
,
Pang K.C.
,
Pavan W.J.
,
Pavesi G.
,
Pesole G.
,
Petrovsky N.
,
Piazza S.
,
Reed J.
,
Reid J.F.
,
Ring B.Z.
,
Ringwald M.
,
Rost B.
,
Ruan Y.
,
Salzberg S.L.
,
Sandelin A.
,
Schneider C.
,
Schoenbach C.
,
Sekiguchi K.
,
Semple C.A.
,
Seno S.
,
Sessa L.
,
Sheng Y.
,
Shibata Y.
,
Shimada H.
,
Shimada K.
,
Silva D.
,
Sinclair B.
,
Sperling S.
,
Stupka E.
,
Sugiura K.
,
Sultana R.
,
Takenaka Y.
,
Taki K.
,
Tammoja K.
,
Tan S.L.
,
Tang S.
,
Taylor M.S.
,
Tegner J.
,
Teichmann S.A.
,
Ueda H.R.
,
van Nimwegen E.
,
Verardo R.
,
Wei C.L.
,
Yagi K.
,
Yamanishi H.
,
Zabarovsky E.
,
Zhu S.
,
Zimmer A.
,
Hide W.
,
Bult C.
,
Grimmond S.M.
,
Teasdale R.D.
,
Liu E.T.
,
Brusic V.
,
Quackenbush J.
,
Wahlestedt C.
,
Mattick J.S.
,
Hume D.A.
,
Kai C.
,
Sasaki D.
,
Tomaru Y.
,
Fukuda S.
,
Kanamori-Katayama M.
,
Suzuki M.
,
Aoki J.
,
Arakawa T.
,
Iida J.
,
Imamura K.
,
Itoh M.
,
Kato T.
,
Kawaji H.
,
Kawagashira N.
,
Kawashima T.
,
Kojima M.
,
Kondo S.
,
Konno H.
,
Nakano K.
,
Ninomiya N.
,
Nishio T.
,
Okada M.
,
Plessy C.
,
Shibata K.
,
Shiraki T.
,
Suzuki S.
,
Tagami M.
,
Waki K.
,
Watahiki A.
,
Okamura-Oho Y.
,
Suzuki H.
,
Kawai J.
,
Hayashizaki Y.
more...
Science309:1559-1563(2005)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain :
C57BL/6J .
tissue :
Hippocampus .
tissue :
Medulla oblongata .
tissue :
Tongue .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain :
FVB/N .
tissue :
Liver .
tissue :
Mammary tumor .
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : TISSUE SPECIFICITY
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : DISRUPTION PHENOTYPE
6.
"A small natural molecule promotes mitochondrial fusion through inhibition of the deubiquitinase USP30."
Yue W.
,
Chen Z.
,
Liu H.
,
Yan C.
,
Chen M.
,
Feng D.
,
Yan C.
,
Wu H.
,
Du L.
,
Wang Y.
,
Liu J.
,
Huang X.
,
Xia L.
,
Liu L.
,
Wang X.
,
Jin H.
,
Wang J.
,
Song Z.
,
Hao X.
,
Chen Q.
more...
Cell Res.24:482-496(2014)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : UBIQUITINATION;DEUBIQUITINATION
7.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : X-RAY CRYSTALLOGRAPHY (2.5 ANGSTROMS) OF 660-735;FUNCTION;SUBUNIT;COILED-COIL DOMAINS