Language:
  
[Sign in] [Register]   

EIAab logo

Index > Protein center > Mfn1(Gene name) > Mouse
  • Add your favorite
  • Mfn1 (Gene name),
  • Mitofusin-1 (Protein name ),  MFN1_MOUSE from NCBI database.
  • top
  • Come back to page head.
  • |
  • General Annotation
  • |
  • Antigen Annotation
  • |
  • 3D
  • |
  • Predicted Eptitope
  • |
  • Vaild Sequence
  • |
  • Related Databases
  • |
  • Feedback
  • Gene name:
    Mfn1;
    Protein name:
    Mitofusin-1;
    Alternative:
    Transmembrane GTPase MFN1;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Forms homomultimers and heteromultimers with MFN2. Multimerization, which is probably mediated by the coiled coil region, may play an essential role in mitochondrion fusion. Participates in a high molecular weight multiprotein complex.
    Function:
    Essential transmembrane GTPase, which mediates mitochondrial fusion. Fusion of mitochondria occurs in many cell types and constitutes an important step in mitochondria morphology, which is balanced between fusion and fission. MFN1 acts independently of the cytoskeleton. Overexpression induces the formation of mitochondrial networks.
    Subcellular Location:
    Mitochondrion outer membrane Multi-pass membrane protein
    Protein Attributes:
    Sequence length:
    741
    Sequence:
    50:
    MAETVSPLKH | FVLAKKAITA | IFGQLLEFVT | EGSHFVEATY | RNPELDRIAS | 
    100:
    EDDLVEIQGY | RNKLAVIGEV | LSRRHMKVAF | FGRTSSGKSS | VINAMLWDKV | 
    150:
    LPSGIGHTTN | CFLSVEGTDG | DKAYLMTEGS | DEKKSVKTVN | QLAHALHMDK | 
    200:
    DLKAGCLVHV | FWPKAKCALL | RDDLVLVDSP | GTDVTTELDI | WIDKFCLDAD | 
    250:
    VFVLVANSES | TLMNTEKHFF | HKVNERLSKP | NIFILNNRWD | ASASEPEYME | 
    300:
    DVRRQHMERC | LHFLVEELKV | VSPSEARNRI | FFVSAKEVLN | SRKHKAQGMP | 
    350:
    EGGGALAEGF | QARLQEFQNF | EQTFEECISQ | SAVKTKFEQH | TIRAKQILDT | 
    400:
    VKNILDSVNV | AAAEKRVYSM | EEREDQIDRL | DFIRNQMNLL | TLDVKKKIKE | 
    450:
    VTEEVANKVS | CAMTDEICRL | SVLVDEFCSE | FHPTPSVLKV | YKSELNKHIE | 
    500:
    DGMGRNLADR | CTNEVNASIL | QSQQEIIENL | KPLLPAGIQN | KLHTLIPCKK | 
    550:
    FDLSYDLNCH | KLCSDFQEDI | VFRFSLGWSS | LVHRFLGSTN | AQRVLLGLSE | 
    600:
    PIFQVPRSLA | STPTAPSNPA | APDNAAQEEL | MITLITGLAS | LTSRTSMGII | 
    650:
    VVGGVIWKTV | GWKLISVTLS | MYGALYLYER | LTWTTRAKER | AFKQQFVNYA | 
    700:
    TEKLQMIVSF | TSANCSHQVQ | QEMATTFARL | CQQVDVTQKH | LEEEIARLSK | 
    741:
    EIDQLEKIQN | NSKLLRNKAV | QLESELENFS | KQFLHPSSGE | S
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    UniGene:
    SMR:
    KEGG:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Mitofusin-1
    Cat.:
    E15253h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Mouse Mitofusin-1
    Cat.:
    E15253m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Mouse Mitofusin-1
    Cat.:
    E15253r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Mitofusin-1
    Cat.:
    U15253r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Mitofusin-1
    Cat.:
    U15253m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Mitofusin-1
    Cat.:
    U15253h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Mouse Mitofusin-1
    Cat.:
    P15253Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Mitofusin-1
    Cat.:
    P15253Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Mitofusin-1
    Cat.:
    P15253Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Mouse Mitofusin-1
    Monoclonal Antibody for Mouse Mitofusin-1
    Monoclonal Antibody for Mouse Mitofusin-1
    Protein for Mouse Mitofusin-1
    Protein for Mouse Mitofusin-1
    Protein for Mouse Mitofusin-1

    R&D Technical Data
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    Precision
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    Recovery
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    Linearity
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    References
    1. 1.
      "Mitofusins Mfn1 and Mfn2 coordinately regulate mitochondrial fusion and are essential for embryonic development."
      Chen H. , Detmer S.A. , Ewald A.J. , Griffin E.E. , Fraser S.E. , Chan D.C.
      J. Cell Biol.160:189-200(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];FUNCTION;DEVELOPMENTAL STAGE;MULTIMERIZATION
      strain: FVB.
    2. 2.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: C57BL/6J.
      tissue: Hippocampus.
      tissue: Medulla oblongata.
      tissue: Tongue.
    3. 3.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: FVB/N.
      tissue: Liver.
      tissue: Mammary tumor.
    4. 4.
      "Membrane topology and mitochondrial targeting of mitofusins, ubiquitous mammalian homologs of the transmembrane GTPase Fzo."
      Rojo M. , Legros F. , Chateau D. , Lombes A.
      J. Cell Sci.115:1663-1674(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY
    5. 5.
      "PINK1-phosphorylated mitofusin 2 is a Parkin receptor for culling damaged mitochondria."
      Chen Y. , Dorn G.W. II
      Science340:471-475(2013) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DISRUPTION PHENOTYPE
    6. 6.
      "A small natural molecule promotes mitochondrial fusion through inhibition of the deubiquitinase USP30."
      Yue W. , Chen Z. , Liu H. , Yan C. , Chen M. , Feng D. , Yan C. , Wu H. , Du L. , Wang Y. , Liu J. , Huang X. , Xia L. , Liu L. , Wang X. , Jin H. , Wang J. , Song Z. , more...
      Cell Res.24:482-496(2014) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: UBIQUITINATION;DEUBIQUITINATION
    7. 7.
      "Structural basis of mitochondrial tethering by mitofusin complexes."
      Koshiba T. , Detmer S.A. , Kaiser J.T. , Chen H. , McCaffery J.M. , Chan D.C.
      Science305:858-862(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.5 ANGSTROMS) OF 660-735;FUNCTION;SUBUNIT;COILED-COIL DOMAINS
    Product Feedback Wall
    Hot Genes
    Atf2 ASPRO ACE ALCAM C19orf80 Trap1a Gdf5
    Top Searches
    Ubiquitin-protein ligase metalloproteinase Ubiquitin ELISA Alpha Tumor necrosis Asprosin TRAP1A
    Why choose EIAAB
    Our products have been quoted by many publications in famous journals such as Cell; Cell Metabolism; Hepatology; Biomaterials.more
    Further Information
    About us Protein center Bank account Distributors Terms & Conditions Career eiaab.com.cn

    Copyright & copy www.eiaab.com2006-2026 All Rights Reserved    EIAab         Email:eiaab@eiaab.com

    鄂ICP备10015095号-1

    鄂公网安备 42018502005535号

    Twitter